Sibutramine tablets, Genesis
Sibutramine tablets, Genesis
- Name: Sibutramine, Genesis
- Effective substance: hydrochloride monohydrate
- Content: 20mg/tab (100 tablets)
- Administration: oral tablets
- Aslso known as: Reductil, Meridia, Siredia, Sibutrex
Sibutramine (usually in the form of the hydrochloride monohydrate salt) is an oral anorexiant. Until 2010 it was marketed and prescribed as an adjunct in the treatment of exogenous obesity along with diet and exercise. It has been associated with increased cardiovascular events and strokes and has been withdrawn from the market in several countries and regions .
Sibutramine was originally developed in 1988 by Boots in Nottingham, UK, and marketed by Knoll Pharmaceuticals after BASF/Knoll AG purchased the Boots Research Division in 1995, and was most recently manufactured and marketed by Abbott Laboratories before its withdrawal from the market. It was sold under a variety of brand names including Reductil, Meridia, Siredia, and Sibutrex.